ea0073aep145 | Calcium and Bone | ECE2021
Lambrinoc Diana
, Roxana Duşceac
, Morea Alexandru
, Cătălina Poiană
IntroductionAdjuvant endocrine therapy has an important role in the management of hormone receptor-positive (expressing oestrogen/progesterone receptors) early-stage breast cancer, reducing the risk of recurrence and improving associated mortality. The estradiol depletion produced by hormone therapy has detrimental effects on skeletal health, which can lead to low bone mineral density (BMD), altered bone microarchitecture and increased risk of fracture.<...